One day after the clinic, a patient named Xiaojing sat in front of me, and asked after asking. Xiaojing was 32 years old. He had been concentrating on work before and did not encounter a suitable object. Now he finally got married.Ready to be a cute baby, hold hands to do a pre -marriage medical examination, but find that HPV52,58 is positive.It is said that the HPV virus is not cured and it is easy to get cervical cancer, but it is not possible to turn in a year or two. What should I do?Can I still get pregnant?In fact, there are many patients like Xiao Jing.Below science in this regard also made this kind of patients not need to be trapped by this.
HPV (Human Papillomavirus, human papilloma virus) is a small group of tiny, envelope -free double -chain DNA virus, which is a Papillomaviridae.HPV is divided into two categories: high -risk (carcinogenic) and low -risk (non -carcinogenic).High -risk HPV is one of the tumor viruses with the closest tumor relationship between human tumors. From the launch of tumors, the entire process of development, development and malignant phenotype is closely related.Almost all (99.7%) cervical cancer is caused by HPV infection.
HPV16 and 18 subtypes are the most closely related to malignant tumors, leading to more than 70%of cervical cancer, 80%of anal cancer, 60%of vaginal cancer, and 40%vulvar cancer.HPV45 and 31 contracted 5%and 10%of cervical cancer, respectively.Low -risk virus is the pathogen of the anal warts of reproductive tract, HPV6 and 11 and 90%of reproductive tract warts and 96%of genital warts.
Women’s HPV infection rates in sexual activity account for 50%-80%. After HPV infection, there are usually no symptoms. Most HPV infections are excessive, and the risk of progress is small.Most HPV removal takes time. About 50%of people may turn overcast within half a year, and the remaining 20%-30%may take 2-3 years to become normal.From chronic sustainable high-risk HPV infection to the final development of malignant tumors, it often takes 10-20 years, but in the exception of a few cases, it can progress as a malignant tumor within 1-2 years.
1.HPV’s impact on fertilization: Most studies believe that HPV infection will not affect fertilization, and female HPV infection itself will not increase the difficulty of conception.Some studies believe that women who accept artificial insemination, the conception rate of HPV positive sperm is only 1/4 of the negative sperm. When men are infected, the living/pregnancy rate is reduced, and the abortion rate increases.Due to limited data, further verification is still required.
2.The impact of HPV infection on the mother: Different studies have found that pregnancy does not cause HPV or LSIL progress.The impact of HPV infection on the ending of pregnancy, reproductive tract infection: HPV infection itself has no obvious correlation with the premature breakthrough of the non -full moon membrane. HPV infection is a sexually transmitted disease, and it is easy to merge other infections of the genital tract, such as bacterial vaginal disease.Vaginal vaginal fake silk yeast disease, chlamydia, chlamydia, etc., these lower genital tract infections are related to bad pregnancy endings. Therefore, HPV positive such as merging infection, which can easily cause premature breakthroughs in the lunar membrane.
Placental infection: Disputes.On the one hand, it believes that HPV infection with nourishing layer cells, damage to the infiltration ability of nourishing cells, abnormal immune regulation of nourishing cells, and promoting HPV replication.Pregnancy ending: limited growth of fetus, early occurrence of eclampsia, abortion and premature birth.There are also the opposite conclusions: the maternal HPV infection does not increase the risk of premature birth and eclampsida, HPV -related high -level cervical lesions are related to premature birth. There is no connection between HPV infection or sacral level lesions and premature birth.
3. The impact of low -risk HPV infection on newborns: Low -risk subtype HPV infection (6, 11) can be transmitted to the baby through maternal and infants during delivery, which can cause neonatal laryngeal papilloma.With the increase of laryngeal nipples, respiratory symptoms, such as extensive lesions, can cause severe respiratory difficulties and deaths; they can also cause damage to soft lane damage during vaginal trials and major bleeding.However, some studies have stated that this chance is small, so it is believed that HPV infection has little effect on pregnancy ending and newborns.Newborns rarely occur in HPV infection. After 6 months of follow -up, HPV infection can naturally turn overcast.
HPV has a pathway such as reproductive cell transmission and prenatal infection. Cester production is not 100 % risk to avoid the risk of newborns infection.
Vaginal delivery does not necessarily cause newborns to infect HPV and cause respiratory papilloma.
HPV has the possibility of spreading the level of breast milk. The existing report is about 2.5%
HPV infection with female pregnancy Suggestions: HPV infection is not an absolute taboo for pregnancy.
my country’s pre -produced health guidelines: Pre -pregnancy health care (before pregnancy) should include cervical coating cytology examination.Cervical cytology screening and HPV testing before pregnancy can be prevented in a timely manner. Early detection, early treatment of cervical cancer, avoiding cervical cancer during pregnancy and being forced to terminate pregnancy.If a patient who does not perform cervical cancer screening within one year before pregnancy, the early screening is also very important, and the relevant examination can be performed within 3 months of pregnancy.
It should be routinely conducting women with pregnancy -induced high -risk HPV typing detection and liquid -based cytological tests. If the test results are positive, it is recommended to check the vulvation of the vulgar lesion and give cervical biopsy.After the cervical disease is cured, consider giving birth.Treatment of genital warts.
HPV positive is not the absolute taboo of pregnancy, but there is no risk of premature fetal membrane, abortion, premature birth, and hypertension during pregnancy, and at the same time there is the risk of newborn infection.
However, the merging cervical cervical lesions, especially the high -level and above lesions, should be treated first, but the cervical treatment caused by it may reduce women’s pregnancy ability, and may induce abortion, premature pregnancy and other bad pregnancy endings.
HPV vaccine: HPV vaccine is used as a first -level prevention of cervical cancer. However, for female patients who have been infected with HPV, HPV vaccines have no treatment effect and have no protective effect on re -infection/damage after treatment.
Pre -pregnancy vaccination has no blocking effect on the vertical transmission of the virus and the mother and baby. It is not recommended to vaccine before pregnancy to prevent maternal and baby transmission.
Vaccine can reduce the risk of semen infection HPV, which helps increase the success rate of ART.
For patients with positive HPV, whether you can prepare for pregnancy, you need to consider:
1.Seeing condyloma acuminatum with the naked eye: Condyloma acuminatum caused by low -risk HPV infection grows rapidly during pregnancy, and pregnancy should be cured.
2.Whether there is a cervical lesion: HPV -positive first confirmed type, such as HPV16, 18, and biopsy if it is necessary. For other high -risk subtypes, refer to the duration of cervical cytology and infection.
3.If the cervical lesions during pregnancy can exclude cervical cancer, you can choose to observe and follow up. If no progress of cervical lesions is found during the follow -up period, the evaluation and treatment of cervical lesions can be delayed to postpartum.
4.Patients of patients with cervical cone surgery are affected by cone cutting length, cone -cut range and surgery and pregnancy interval time.There is no need to perform conventional cervical rings for patients with cervical cone operation.
HPV infection has more factors, which is of course the best for pregnancy after turning over.HPV does not turn overcast, TCT is normal or the colposcopy evaluation is normal or the cervical biopsy is normal. The main complaint and the infection of the reproductive tract (including condyloma acuminatum) are not taboos of pregnancy.
Gynecology: Su Yanyan
“”@Headline health
