Biochemical pregnancy refers to an early abortion that occurs within 5 weeks of pregnancy. The HCG can be detected in the blood, which is more than 25 mLU/ml or a positive urine pregnancy test.Known as the "sub -clinical abortion".So why do IVFAs also have biochemical pregnancy?
First, let’s start with the embryo bed
During natural pregnancy, sperm and eggs are combined with fertilization in the fallopian tube. The fertilized eggs are transported to the uterine cavity through the peristalsis of the fallopian tube, and gradually develop into embryo sacs or bubbles.At the same time, endometrium is also actively preparing to welcome the embryo. When the development pace of embryo and endometrium is consistent, the bubbles and endometrium in the acceptance state will further contact.
For 7 to 8 days, the bubbles drilled into the endometrium layer of the uterine. The embryo nourishing layer and the endometrium eventually established an intimate connection. This is the embryo’s bed.In the process of test tube babies, the oval embryo that develops to the third day, or the blastocyst that develops to the fifth day, will be transplanted directly into the uterine cavity and starts to bed in the embryo.
Like natural pregnancy, IVF may also have an embryonic bed failure, and biochemical pregnancy occurs.There are almost 6 reasons for IVF biochemical pregnancy.
1. The fertilized egg itself is defective
Generally speaking, abnormal embryo chromosomes may be the main cause of biochemical pregnancy.In the early three months of pregnancy, more than 50%of the causes of abortion were chromosomal abnormalities.Unless it is the third -generation test tube technology, conventional IVF technology cannot be learned from the appearance whether the chromosome is abnormal.
2. Episoal luteum functional incomplete function
Instead of luteal function, it can cause insufficient luteal secretion, abnormal endometrium, and affect the implantation of fertilized eggs in the uterus.Although IVF has conventional luteal support, due to individual differences such as drug doses and drug absorption, 100%cannot guarantee pregnancy ending.
3. Uterine factors
Uterine dysplasia, thin endometrium, submucosal fibroids, endometrium polyps, uterine cavity adhesion, endometrial tuberculosis and other factors all affect the implantation of fertilized eggs.Therefore, it is best to deal with these uterine abnormal factors before doing test tubes (especially before embryo transplantation), and try to provide an ideal "hotbed" for the embryo.
4. Immune factors
Sperm, sperm, or fertilized eggs are antigen substances. After being absorbed by the vagina and uterine epithelium, antibody substances are generated by immune response, so that sperm and eggs cannot be combined or fertilized eggs cannot be imposed.
5. External factors
Smoking (including second -hand smoke), drinking, contact with chemical poisons, severe noise and vibration, emotional excitement, high temperature environment, etc., can cause placenta and fetus damage and cause miscarriage.
6. Disease and virus
Female friends have infections such as high fever, viruses, and sepsis before and after pregnancy, which will affect the development of eggs and fertilized eggs and cause miscarriage.Therefore, good pregnancy angels recommend that necessary sports before pregnancy to enhance physical fitness.
In a place where I do n’t know the embryo bed, it is impossible to rule out whether it is in other parts outside the fallopian tube or uterus. Is it a abortion of an ectopic pregnancy?Hey, IVF does not completely avoid ectopic pregnancy.The occasional biochemical pregnancy is mostly the poor quality of the embryo itself, or the accidental factors cause fertilized egg chromosomal variations, and the survival of the fittest is eliminated.
Therefore, accidents should not be too nervous when you have a biochemical pregnancy occasionally. Continue to transplant next time, but repeated biochemical pregnancy, then consider embryo transplantation after treatment.
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